NINDS Peripheral Neuropathy Information = Page

From: Subject: NINDS Peripheral Neuropathy Information Page Date: Thu, 4 Mar 2004 17:42:11 -0800 MIME-Version: 1.0 Content-Type: multipart/related; boundary="----=_NextPart_000_0023_01C40210.06347550"; type="text/html" X-MimeOLE: Produced By Microsoft MimeOLE V6.00.2800.1165 This is a multi-part message in MIME format. ------=_NextPart_000_0023_01C40210.06347550 Content-Type: text/html; charset="iso-8859-1" Content-Transfer-Encoding: quoted-printable Content-Location: http://www.ninds.nih.gov/health_and_medical/disorders/peripheralneuropathy_doc.htm NINDS Peripheral Neuropathy Information = Page

National Institute of Neurological Disorders and = Stroke		Accessible=20 version
	=20	<= IMG=20 height=3D20 alt=3D"NINDS Disorder Information"=20 src=3D"http://www.ninds.nih.gov/img/disorders_selected.gif" = width=3D79=20 border=3D0>	=20

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3D"NINDS

Science=20 for the Brain The nation's leading supporter of = biomedical=20 research on disorders of the brain and nervous system =

<= FONT=20 face=3D"Arial, Helvetica, sans-serif" color=3D#ffffff = size=3D2>Browse all=20 disorders

Browse all=20 health
organizations

More=20 about
Peripheral = Neuropathy

Studies with = patients

Research=20 literature

Press=20 releases

Disclaimer

Contact=20 us

My=20 privacy=20

NINDS is part of the
National Institutes=20 of
Health

NINDS=20 Peripheral Neuropathy Information Page

Reviewed=20 12-01-2003

Get=20 Web page suited for printing
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Table of Contents (click to jump to sections)

What=20 is Peripheral Neuropathy?
Is=20 there any treatment?
What=20 is the prognosis?
What=20 research is being done?

Organizations
Related=20 NINDS Publications and Information
Additional=20 resources from = MEDLINEplus

What is Peripheral=20 Neuropathy?
Peripheral neuropathy describes damage to the=20 peripheral nerves, the vast communications network that transmits=20 information from the brain and spinal cord to every other part of = the=20 body. It may be caused by diseases of the nerves or as the result = of=20 systemic illnesses. Many neuropathies have well-defined causes = such as=20 diabetes, uremia, AIDs, or nutritional deficiencies. In fact, = diabetes is=20 one of the most common causes of peripheral neuropathy. Other = causes=20 include mechanical pressure such as compression or entrapment, = direct=20 trauma, penetrating injuries, contusions, fracture or dislocated = bones;=20 pressure involving the superficial nerves (ulna, radial, or = peroneal)=20 which can result from prolonged use of crutches or staying in one = position=20 for too long, or from a tumor; intraneural hemorrhage; exposure to = cold or=20 radiation or, rarely, certain medicines or toxic substances; and = vascular=20 or collagen disorders such as atherosclerosis, systemic lupus=20 erythematosus, scleroderma, sarcoidosis, rheumatoid arthritis, and = polyarteritis nodosa. A common example of entrapment neuropathy is = carpal=20 tunnel syndrome, which has become more common because of the = increasing=20 use of computers. Although the causes of peripheral neuropathy are = diverse, they produce common symptoms including weakness, = numbness,=20 paresthesia (abnormal sensations such as burning, tickling, = pricking or=20 tingling) and pain in the arms, hands, legs and/or feet. A large = number of=20 cases are of unknown cause.

Is there any=20 treatment?
Therapy for peripheral neuropathy differs = depending on=20 the cause. For example, therapy for peripheral neuropathy caused = by=20 diabetes involves control of the diabetes. In cases where a tumor = or=20 ruptured disc is the cause, therapy may involve surgery to remove = the=20 tumor or to repair the ruptured disc. In entrapment or compression = neuropathy treatment may consist of splinting or surgical = decompression of=20 the ulnar or median nerves. Peroneal and radial compression = neuropathies=20 may require avoidance of pressure. Physical therapy and/or splints = may be=20 useful in preventing contractures (a condition in which shortened = muscles=20 around joints cause abnormal and sometimes painful positioning of = the=20 joints).

What is the=20 prognosis?
Recovery from peripheral neuropathy is usually = slow.=20 Depending on the type of peripheral neuropathy, the patient may = fully=20 recover without residual effects or may partially recover and have = sensory, motor, and vasomotor (blood vessel) deficits. If severely = affected, the patient may develop chronic muscular atrophy.

What research is = being=20 done?
The NINDS supports a broad program of research on = disorders=20 of the peripheral nervous system, including peripheral neuropathy. = Much of=20 this research is aimed at increasing the understanding of = peripheral=20 neuropathy and finding ways to prevent and cure the disorder.

Select this link to view a list of studies = currently=20 seeking patients.

Organizations

American Chronic Pain Association (ACPA)
P.O. Box 850 =
Rocklin, CA 95677-0850
ACPA@pacbell.net
http://www.theacpa.org/
Tel:=20 916-632-0922 800-533-3231
Fax: 916-632-3208

National Chronic Pain Outreach Association = (NCPOA)
P.O. Box=20 274
Millboro, VA 24460
ncpoa@cfw.com
http://www.chronicpain.org/
T= el:=20 540-862-9437
Fax: 540-862-9485

Neuropathy Association
60 East 42nd Street
Suite = 942=20
New York, NY 10165-0999
info@neuropathy.org
http://www.neuropathy.org/
Tel= :=20 212-692-0662 800-247-6968
Fax: 212-692-0668

National Foundation for the Treatment of Pain
P.O. = Box 70045=20
Houston, TX 77270
markgordon@paincare.org =
http://www.paincare.org/
Tel:=20 713-862-9332
Fax: 713-862-9346

American Pain Foundation
201 North Charles Street =
Suite=20 710
Baltimore, MD 21201
info@painfoundation.org =
http://www.painfoundation.org/
Tel:=20 888-615-PAIN (7246) 410-783-7292
Fax: 410-385-1832

National Institute of Diabetes and Digestive and Kidney = Diseases:=20 National Kidney & Urologic Diseases Information
3 = Information=20 Way
Bethesda, MD 20892-3580
nkudic@info.niddk.nih.gov=20
http://www.nid= dk.nih.gov/health/kidney/nkudic.htm
Tel:=20 301-654-4415 800-891-5390 800-575-9355

Related NINDS = Publications=20 and Information

Pain =97 Hope Through Research
Information booklet on = pain=20 compiled by the National Institute of Neurological Disorders and = Stroke=20 (NINDS).

NINDS = health-related=20 material is provided for information purposes only and does not=20 necessarily represent endorsement by or an official position of = the=20 National Institute of Neurological Disorders and Stroke or any = other=20 Federal agency. Advice on the treatment or care of an individual = patient=20 should be obtained through consultation with a physician who has = examined=20 that patient or is familiar with that patient's medical=20 history.

All NINDS-prepared information is in the public domain and may = be=20 freely copied. Credit to the NINDS or the NIH is appreciated.

Provided = by:
The=20 National Institute of Neurological Disorders and Stroke =
National=20 Institutes of Health
Bethesda, MD = 20892

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Home | About = NINDS | <= EM>Disorders=20 | Funding | = News & = Events=20 | Find = People | Jobs & = Training | Acce= ssibility=20
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